MersV1, Main, Exploration, bibRecord, 000640

Crystallization and Structural Determination of the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

Identifieur interne : 000640 ( Main/Exploration ); précédent : 000639; suivant : 000641

Crystallization and Structural Determination of the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

Auteurs :

Source :

MERS Coronavirus ; 2019.

RBID : PMC:7123399

Abstract

Three-dimensional structures of the receptor-binding domain (RBD) of MERS-CoV spike glycoprotein bound to cellular receptor and monoclonal antibodies (mAbs) have been determined by X-ray crystallography, providing structural information about receptor recognition and neutralizing mechanisms of mAbs at the atomic level. In this chapter, we describe the purification, crystallization, and structure determination of the MERS-CoV RBD.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123399

DOI: 10.1007/978-1-0716-0211-9_4
PubMed: 31883086
PubMed Central: 7123399

Affiliations:

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Crystallization and Structural Determination of the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

Crystallization and Structural Determination of the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

Source :

Abstract

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